About Temazepam

About Temazepam

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Use Warning/Monitor. Ethinyl estradiol may perhaps inhibit the clearance of benzodiazepines that undertake oxidation, thereby expanding serum concentrations of concomitantly administered benzodiazepines.

darifenacin will enhance the degree or result of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.

quinupristin/dalfopristin will raise the level or influence of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

These brokers should really only be mixed if choice procedure choices are inadequate. If blended, Restrict the dosages and period of each drug. Take into consideration therapy modification

With medicine inhibiting CYP3A into a lesser, but still major degree, estazolam ought to be used only with warning and thought of appropriate dosage reduction. The subsequent are examples of prescription drugs regarded to inhibit the metabolism of other similar benzodiazepines, presumably by way of inhibition of CYP3A: nefazodone, fluvoxamine, cimetidine, diltiazem, isoniazide, and a few macrolide antibiotics.

Limit dosages and durations to your minimal expected. Comply with patients for symptoms and signs and symptoms of respiratory despair and sedation.

fosamprenavir will improve the amount or result of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

omaveloxolone will decrease the extent or outcome of triazolam by affecting hepatic/intestinal enzyme CYP3A4 Trazodone metabolism. Use Caution/Check. Omaveloxolone may perhaps reduce systemic exposure of delicate CYP3A4 substrates. Verify prescribing facts of substrate if dosage modification is needed.

Coadministration with benzodiazepines which might be thoroughly metabolized by CYP3A4 could induce big boosts in the concentration of those benzodiazepines, maybe leading to critical and/or everyday living -hreatening activities (eg, extended or amplified sedation or respiratory depression)

danazol will raise the stage or influence of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

marijuana will raise the stage or influence of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

Benzodiazepines interact at GABAA websites and opioids interact generally at mu receptors. When benzodiazepines and opioids are merged, the prospective for benzodiazepines to significantly worsen opioid-linked respiratory depression exists.

The upper estazolam doses were remarkable to placebo in most EEG actions of sleep induction and servicing, especially for the 2 mg dose, but just for slumber length in subjective steps of sleep.

chloramphenicol will boost the level or effect of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.